Hypertension or High Blood Pressure (“HBP”) is known as “the silent killer.” Most HBP sufferers don’t know they have it, and even those who do know often avoid standard drug therapies because of their negative side effects.

HBP is a pervasive medical condition in which the long-term force of the elevated blood pressure against arterial walls eventually causes profound health problems, including heart disease.

Hypertension develops over many years, and it eventually affects nearly everyone: An estimated 70 million adult Americans (29%) have high blood pressure (REF?!?), as do more than 1 billion hypertension sufferers, worldwide (REF?!?). Genetic factors, as well as diet, life-style, lack of regular exercise and age are all risk factors for hypertension, which is an asymptotic disease–treatable but not curable–and as a function of age, it is more prevalent in older adults.

Reducing hypertension can save hundreds of thousands of lives and save billions of dollars in healthcare:  Total costs associated with high blood pressure in 2011 in the U.S. were $46 billion in health care services, medications, and missed days of work.

“In a May, 2011 meta-analysis that included 464,000 people, the authors showed that for a reduction of only 10 mmHg systolic or 5 mmHg diastolic, there was a 22% reduction in coronary heart disease events and a 41% reduction in stroke.*

Diabetes Care, May 2011. Blood Pressure: The Lower, the Better

How Does It Work in Your Body?

The thermo-neurostimulator (controlled cold tip), when topically applied to the surface of the neck at the carotid sinus location, activates baroreceptors located on the carotid artery, for a precise duration. The nerves connected to these activated baroreceptors carry messages, via afferent fibers, to the brain (hypothalamus), which then stimulates the parasympathetic nervous system involving the vagus nerve. Activation of the parasympathetic nervous system causes:

(a) Vasodilation of the peripheral arteries and veins; and
(b) Lowering of the user’s pulse, i.e., slowing of the heart rate.

The combined effect results in lowering of the user’s blood pressure. Daily use of the device for 30 to 35 days can result in the 24-hour sustainable lowering of HBP, which indicates that the parasympathetic nervous system has been conditioned to maintain vasodilation and the lowered heart rate.

Blood pressure is determined by the amount of blood your heart pumps and the amount of resistance to blood flow in your arteries. The more blood your heart pumps and the narrower your arteries, the higher your blood pressure.

In our pilot clinical trial conducted with 60 patients over 68 days, a typical patient had a systolic BP of 176 mmHg. After his first PhysioCue therapy session, his BP dropped to 155 mmHg. Daily 5-minute therapy sessions produced similar results, and his sustainable BP steadily dropped to 134 mmHg— a total reduction of 42 mmHg.

Results from a major heart study showed that the benefit of reducing blood pressure, by even a few mmHg, leads to significant reductions in the risk of coronary heart disease and stroke incidents: “A reduction in diastolic blood pressure of only 2 mmHg leads to a 9% reduction in coronary heart disease, and a 15% reduction in stroke incidents.  A 7.5 mmHg reduction leads to a 29% reduction of coronary heart disease, and a 48% reduction in stroke incidents.*